About IGM Biosciences, Inc.
IGM Biosciences (Nasdaq: IGMS) is a clinical-stage biotechnology company committed to developing and delivering a new class of medicines to treat patients with autoimmune and inflammatory diseases. The Company’s pipeline of clinical and preclinical assets is based on the IgM antibody, which has 10 binding sites, compared to conventional IgG antibodies with only 2 binding sites. We have created unique IgM antibodies with high selectivity, affinity, and avidity that may redefine what is possible for therapeutic antibody medicines. We are committed to exploring how the unique structure and binding properties of the IGM antibody can improve outcomes for patients with these serious conditions. The Company also has an exclusive worldwide collaboration agreement with Sanofi to create, develop, manufacture, and commercialize IgM antibody agonists against oncology, immunology, and inflammation targets. For more information, please visit www.igmbio.com.
Imvotamab in Autoimmune and Inflammatory Diseases
Imvotamab is a bispecific T cell engaging IgM antibody targeting CD20 and CD3 proteins. We believe that Imvotamab, with its 10 binding units for CD20, may successfully bind to CD20 expressing B cells with more power (avidity) compared to an IgG bispecific antibody with only one or two binding units for CD20. Our preclinical studies suggest that Imvotamab may offer the potential for deeper depletion of B cells, including those in low CD20 expressing cells, than currently approved antibody therapies. We are evaluating Imvotamab in Phase 1b clinical trials of Imvotamab in severe systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and idiopathic inflammatory myopathies (myositis).
Position:
We seek a highly motivated and innovative scientist with immunology research experience and a passion to develop antibody-based therapeutics. You will play an integral role in the pre-clinical development of novel autoimmunity and inflammation therapeutics. The ideal candidate will have a proven track record of experience with core immunological assays and models (e.g., T cell proliferation, antigen recall, in vivo models of inflammatory disease) and techniques (immune cell culture, flow cytometry, ELISA, RT-PCR, etc.) The candidate will be required to coordinate and execute on research projects across multiple functional teams, both internal of IGMS and external vendors and collaborators. Strong communication skills and organizational skills are essential. A key initial responsibility will be the set up and establishment of core capabilities in the AI lab. This role involves delivering on programs through proof- of-concept in vitro and in vivo studies and advancing therapeutic candidates from early discovery to IND- enabling studies.
We offer a fast-paced, collaborative, team-based work environment.
One of our top priorities is to maintain our employees' and their families' health and well-being. To achieve this goal, we offer comprehensive benefits with a variety of options:
Medical, dental, and vision insurance.
IGM covers the full premium amount for our employees and their dependents
FSA (Flexible Spending Account) or HSA (Health Savings Account)
STD, LTD, Basic Life and AD&D Insurance, Supplemental Life and AD&D Insurance
Voluntary Life Insurance and Disability
401(k) Plan with Employer Match
3 Weeks of Paid Time Off, 5 sick days per year, 12 holidays
Cell phone & internet subsidy
Employee Referral Bonus Program
Annual training budget for professional development
Commuter Benefit
Pet Insurance
Annual bonus program
New hire equity
Annual refresh grants
ESPP (Employee Stock Purchase Plan)
IGM is an equal opportunity employer that prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status. All qualified applicants will be considered for employment.
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Join IGM Biosciences as a Scientist III in Doylestown, PA, where your innovative spirit and immunology expertise will be at the forefront of advancing novel therapeutics targeting autoimmune and inflammatory diseases. At IGM, we pride ourselves on developing unique IgM antibodies with exceptional binding capabilities, and as a Scientist III, you'll play a key role in this endeavor. Your responsibilities will include establishing core capabilities within our AI lab and leading research efforts to generate proof-of-concept data through in vitro and in vivo studies. Collaborating with cross-functional teams, you'll help guide therapeutic candidate selection and conduct IND-enabling studies, pushing the boundaries of current treatments available in the market. We’re seeking someone with a Ph.D. or equivalent hands-on experience in immunology or a related field. If you’re adept in core techniques, including flow cytometry, cell culture, and immune assays, and have strong organizational and communication skills, this is the perfect opportunity to contribute to cutting-edge research while making meaningful impacts on patient outcomes. Embrace the chance to work in a dynamic and supportive environment, where your contributions fuel collaborative success and innovation every day. With competitive compensation and comprehensive benefits, IGM Biosciences is dedicated to fostering your career growth while ensuring the well-being of our employees and their families.
About IGM Biosciences: Headquartered in Mountain View, California, IGM Biosciences is a clinical-stage biotechnology company focused on creating and developing IgM antibodies. IGM Biosciences has worked to overcome the manufacturing and protein en...
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