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Scientist II

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on XFacebookInstagramYouTubeLinkedIn and Tik Tok.

Job Description

Purpose/Primary Job Function

The Quantitative Translational ADME Science Department (QTAS) at AbbVie in Worcester, MA is seeking an experienced, independent, creative, and highly motivated scientist to join our non-regulated bioanalytical team. The candidate will conduct preclinical/clinical PK and biomarker assay development and validation as well as sample analysis to support discovery and early development activities of novel therapies in multiple therapeutic areas. The ideal candidate should have hands-on experience in a variety of technologies, including but not limited to ligand binding assays (LBA) on various platforms (ELISA, MSD), quantitative and digital PCR, branched DNA analysis and pre-analytical workflow optimization (sample processing steps), etc. He/she will be a key member of a large molecule PK and biomarker bioanalysis teams supporting all AbbVie therapeutic areas with fit-for-purpose methods to enable discovery and development stage activities. The candidate will identify and optimize assay formats, conduct sample analysis, troubleshoot, and communicate results to key project team members including modelers to advance decision making and candidate drug nominations.

Responsibilities

  • Develop, validate, communicate and troubleshoot bioanalytical assays across a variety of platforms (LBA, PCR, etc) and sample matrices (serum and tissues).
  • Lead assay planning and execution of pre-clinical in vivo and exploratory human sample analysis based on bioanalytical protocol and study design.
  • Conduct, and document appropriately compliant biomarker sample testing to support non-clinical and clinical (exploratory) studies.
  • Develop and lead effective partnerships with discovery, preclinical safety, precision medicine, clinical pharmacology, and project team representatives in a highly collaborative and innovative environment to deliver high-impact and quality data in a timely manner.

Qualifications

Qualifications

Education/Experience

  • A minimum of 7+ years of working experience with bachelor’s degree in molecular biology, biochemistry, or other related fields, or 5+ years of experience with Master’s, or PhD degree in relevant fields.
  • Proficient in LBA (ELISA, MSD, etc.), molecular biology, and genomics related assays, method development, validation, and sample testing workflows to comply with current regulatory standards and best industry practices.
  • Experience in electronic notebooking and data management (LIMS) systems required
  • Excellent communication, time management, and prioritization skills, and proven ability to work effectively as a member of a multidisciplinary team.
  • Demonstrated capacity to work in a fast-paced environment with meticulous attention to detail, and an ability to handle multiple projects, prioritize work, and meet deadlines.
  • Author of relevant publications and reports on bioanalytical assays and drug development fields.

Preferred:

  • Experience with automation platforms (Hamilton, Tecan) is a plus

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​

  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

  • This job is eligible to participate in our short-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html 

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

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Average salary estimate

$110000 / YEARLY (est.)
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$90000K
$130000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

What You Should Know About Scientist II, AbbVie

At AbbVie, we're on a mission to innovate and create solutions that tackle serious health challenges. As a Scientist II at our Worcester, MA location, you'll take the lead in developing and validating bioanalytical assays that play a crucial role in the development of our novel therapies. Imagine working in a dynamic environment, collaborating with cross-functional teams where your insights will directly contribute to the advancement of cutting-edge treatments across therapeutic areas such as immunology, oncology, and neuroscience. You'll utilize your expertise in various technologies including ligand binding assays (LBA), digital PCR, and more to conduct preclinical and clinical studies. Our ideal candidate is someone who's not only knowledgeable but also creative and highly motivated, with at least 7 years of experience in the field. This position will challenge you to think critically, troubleshoot effectively, and communicate your findings to inform crucial decisions in drug development. Join us, and become a key player in our mission to transform lives through science. Help us bring the future of healthcare closer, one assay at a time!

Frequently Asked Questions (FAQs) for Scientist II Role at AbbVie
What qualifications are required for the Scientist II position at AbbVie?

For the Scientist II role at AbbVie, candidates must possess at least a bachelor’s degree in molecular biology, biochemistry, or related fields with a minimum of 7 years of relevant experience. Alternatively, a Master’s degree plus 5 years of relevant experience or a PhD degree can also qualify applicants. Proficiency in various assays, strong communication skills, and a collaborative mindset are essential.

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What kind of technologies will I work with as a Scientist II at AbbVie?

As a Scientist II at AbbVie, you will have the opportunity to work with numerous technologies vital to bioanalytical assays. Your experience with ligand binding assays (LBA), digital PCR, and branched DNA analysis will be key as you conduct sample analysis and optimize assay formats across various platforms. This diverse tech exposure enriches your skill set and enhances AbbVie's ability to deliver impactful therapies.

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What will my daily responsibilities look like as a Scientist II at AbbVie?

In the Scientist II position at AbbVie, you can expect a variety of responsibilities each day. You'll develop, validate, and troubleshoot bioanalytical assays, plan assay execution for pre-clinical studies, and communicate results with project teams. You’ll play a pivotal role in supporting the drug development process, working collaboratively to ensure accuracy, compliance, and timely delivery of quality data.

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What career development opportunities are available for Scientist II at AbbVie?

AbbVie places a strong emphasis on professional growth and development. As a Scientist II, you’ll have access to various resources for career advancement, including mentorship programs, training sessions on emerging technologies, and chances to lead projects. AbbVie encourages a culture of innovation where your contributions are valued, paving the way for progression within the organization.

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How does AbbVie support work-life balance for its employees?

At AbbVie, we understand the importance of work-life balance. We offer flexible work schedules, comprehensive benefits, and a supportive work environment. The company strives to ensure that you maintain a fulfilling personal life while achieving your professional goals, allowing you to bring your best self to work every day.

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What culture should I expect while working at AbbVie?

AbbVie fosters a culture of diversity, inclusion, and collaboration. As a Scientist II here, you will work in a highly collaborative environment where innovation is encouraged, and diverse perspectives are valued. Teamwork is key, and you can expect to engage with various disciplines to achieve shared goals and contribute to the company’s mission of transforming health care.

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What are the career prospects for a Scientist II at AbbVie?

The career prospects for a Scientist II at AbbVie are robust. With demonstrated success and performance, you can progress to senior scientist roles or take on leadership responsibilities within project teams. The company's commitment to employee development opens various pathways, encouraging lateral and upward movement within the organization.

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Common Interview Questions for Scientist II
Can you describe your experience with ligand binding assays at AbbVie?

When discussing your experience with ligand binding assays (LBA), focus on specific techniques you've employed, challenges you've overcome, and successful outcomes from your projects. Share quantitative results and how your findings impacted drug development. Highlighting your proficiency and practical applications will demonstrate your value to AbbVie.

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How do you ensure compliance with regulatory standards in your bioanalytical work?

To ensure compliance with regulatory standards, I prioritize understanding the relevant guidelines and staying updated with the latest industry practices. During interviews, describe specific protocols you have implemented, your experience in documentation, and how you conduct quality checks on your assays to meet compliance criteria in various projects.

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Tell us about a time you faced a significant challenge in assay development and how you handled it?

Draw on a specific example where you encountered a significant hurdle in assay development. Explain the problem, your thought process in resolving it, and the solution you implemented. Focus on your analytical skills and resilience, showcasing how you transformed the challenge into a learning opportunity that led to successful outcomes.

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How do you prioritize multiple projects at once in a fast-paced environment?

When asked about prioritization, discuss your time management strategies, such as creating schedules, setting clear goals for each project, and using digital tools to track progress. Illustrate how this approach has allowed you to meet deadlines without compromising quality, demonstrating your ability to remain effective under pressure.

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What bioanalytical techniques are you most proficient in, and why?

In your response, highlight the bioanalytical techniques you excel in, such as ELISA or quantitative PCR. Provide examples of specific projects in which you've utilized these techniques, discussing how your expertise contributed to successful outcomes. Emphasizing your depth of knowledge will reinforce your qualifications as a Scientist II.

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Describe your experience collaborating with other departments like clinical pharmacology?

Share specific instances where collaboration with clinical pharmacology or other departments was essential. Discuss how communication, teamwork, and leveraging diverse expertise led to solutions that drove project success. Illustrate your ability to develop strong interdepartmental relationships that lead to impactful research.

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How do you stay current with advancements in bioanalytical technologies?

Staying updated on advancements in bioanalytical technologies is crucial. Discuss how you follow relevant journals, attend conferences, participate in webinars, and engage with professional communities. Highlight your commitment to continuous learning, showcasing how you can apply new knowledge to your work at AbbVie.

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What is your approach to troubleshooting assays that don’t yield expected results?

For troubleshooting assays, emphasize your systematic approach: identify the problem, analyze potential causes, and develop hypotheses. Provide an example of a time when you successfully troubleshot an assay, detailing the steps taken and the resolution achieved. This demonstrates your analytical mindset and determination.

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How do you manage your time and ensure you meet deadlines?

Discuss your time management techniques, such as journal keeping, setting deadlines for specific tasks, and regularly reviewing progress. Offer insight into how these practices have consistently allowed you to deliver projects on time while maintaining high-quality standards, reinforcing your reliability as a candidate.

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Why do you want to work at AbbVie as a Scientist II?

In your answer, articulate your passion for AbbVie’s mission and how your background aligns with the company's objectives in developing innovative therapies. Discuss specific projects or initiatives you admire at AbbVie and how you see yourself contributing to the team and the company's broader goals.

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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: i...

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