Technical Project Manager

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary tests, vast data sets and advanced analytics. The Guardant Health oncology platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has commercially launched Guardant360®, Guardant360 CDx, Guardant360 TissueNext™, Guardant360 Response™, and GuardantOMNI® tests for advanced stage cancer patients, and Guardant Reveal™ for early-stage cancer patients. The Guardant Health screening portfolio, including the Shield™ test, aims to address the needs of individuals eligible for cancer screening.

We are seeking a highly organized and detail-oriented Technical Project Manager to drive execution across multiple scrum teams and ensure the successful delivery of key initiatives. This individual will play a pivotal role in orchestrating Agile processes, facilitating collaboration between Product, Engineering, and key stakeholders, and ensuring projects stay on track from ideation to launch.

A strong attention to detail and proficiency in Agile methodologies, project tracking, and communication tools are essential for success in this role.

Key Responsibilities

Agile Execution & Scrum Leadership

● Lead and facilitate scrum ceremonies including sprint planning, daily stand-ups, sprint reviews, and retrospectives.

● Work with Product and Engineering teams to define and establish sprint goals and ensure clear alignment with the overall roadmap.

● Remove blockers, identify dependencies, and ensure teams stay focused on execution.

Project Planning & Roadmap Visibility

● Create and maintain visibility into the roadmap, ensuring stakeholders have clear insight into project milestones, target launch dates, and dependencies.

● Track progress against launch timelines and proactively identify risks, escalating when necessary.

● Partner with Product Managers and Engineering leads to align priorities, scope, and deliverables.

Process Optimization & Tooling

● Leverage Jira, Confluence, and other Agile tools to track progress, manage backlog refinement, and ensure accurate reporting.

● Establish and enforce the best practices for sprint planning, release management, and delivery tracking.

● Continuously evaluate and refine project management processes to improve team efficiency and collaboration.

Stakeholder Collaboration & Communication

● Act as the bridge between Engineering, Product, and business stakeholders, ensuring seamless communication and alignment.

● Provide regular status updates, reports, and presentations on project progress, risks, and mitigation plans.

● Facilitate cross-team collaboration, ensuring dependencies are managed and expectations are clearly set.

● 7+ years of experience as a Technical Project Manager, Agile Project Manager, or Scrum Master in a software development environment.

● Proven ability to drive Agile development processes and scrum teams in a fast-paced, cross-functional environment.

● Strong proficiency in Jira, Confluence, and Agile project tracking tools.

● Experience establishing sprint goals, managing sprint backlog, and tracking progress against launch timelines.

● Excellent attention to detail, problem-solving skills, and ability to identify and mitigate risks.

● Strong verbal and written communication skills, with the ability to engage both technical and non-technical stakeholders.

Nice to Have

● Experience in Life Sciences, Healthcare, or HealthTech industries.

● Familiarity with EMR/EHR integrations (Epic, OncoEMR, HL7, FHIR).

● Background in cloud-native applications, DevOps, and CI/CD best practices.

Hybrid Work Model: At Guardant Health, we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

For positions based in Palo Alto, CA, the base salary range for this full-time position is $147,440 to $207,350. The range does not include benefits, and if applicable, bonus, commission, or equity.

Within the range, individual pay is determined by work location and additional factors, including, but not limited to, job-related skills, experience, and relevant education or training. If you are selected to move forward, the recruiting team will provide details specific to the factors above.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to [email protected]

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.

Please visit our career page at: http://www.guardanthealth.com/jobs/