Senior Technical Project Manager, Machine Learning Science

About Us

Deep Genomics is at the forefront of using artificial intelligence to transform drug discovery. Our proprietary AI platform decodes the complexity of genome biology to identify novel drug targets, mechanisms, and genetic medicines inaccessible through traditional methods. We co-develop drug programs and AI models with partners and internally, and pursue major technology builds with pharmaceutical partners. With expertise spanning machine learning, bioinformatics, data science, engineering, and drug development, our multidisciplinary team located in Toronto, Cambridge, MA, and select other sites is revolutionizing how new medicines are created.

Where You Fit In

As a Senior Technical Project Manager on the Machine Learning Science (ML Science) team, you will lead the execution of complex, cross-functional projects at the intersection of machine learning, genome biology, and drug discovery. You’ll play a pivotal role in helping our teams build and deploy ML models that enable key scientific breakthroughs in target identification, molecule design, and therapeutic optimization.

You’ll partner closely with a broad range of stakeholders — including ML Scientists, Bioinformaticians, Statistical Geneticists, Experimental Biologists, Product Managers, Engineers, and Leadership — to ensure ML projects are well-scoped, prioritized, and delivered effectively. These initiatives span internal model development and high-impact external collaborations, including pharmaceutical partnerships, and require tight coordination across both technical and scientific teams.

You will report to the Chief Innovation Officer, Brendan Frey, and work with teams across Machine Learning, Target Identification, Engineering, Platform Biology, Platform Technology, Platform Chemistry, Legal, Drug Discovery, and Alliances & Partnerships to drive the successful execution of our ML development goals. This hybrid role is based in Toronto, and candidates must be located in or able to relocate to Toronto or the Greater Toronto Area (GTA).

• Lead the planning, execution, and delivery of machine learning projects across internal R&D and strategic partnerships.
• Drive quarterly and yearly project planning with ML Scientists and cross-functional stakeholders; define clear goals, outcomes, timelines, and resource needs.
• Establish and maintain robust project management practices tailored to agile, iterative ML workflows.
• Track progress across multiple concurrent initiatives; identify risks and proactively remove blockers to keep teams on track.
• Facilitate strong collaboration across research, engineering, and external partner teams.
• Ensure clear, timely communication of project status, milestones, and risks to internal and external stakeholders.
• Manage and facilitate strategic collaborations with external partners, ensuring alignment, execution, and progress on ML and data-driven initiatives.

• 5+ years of experience in Technical Project Management, including leading complex, multi-stakeholder projects from planning through execution.
• Proven experience working with ML or Data Science teams; familiarity with the ML lifecycle, including model training, evaluation, and deployment.
• Exceptional organizational and communication skills, with experience engaging stakeholders from engineering, research, and leadership.
• Experience working in agile, cross-functional teams.
• Comfort operating in a fast-paced, research-driven environment where priorities evolve based on new data and discovery.
• Strategic thinking and attention to detail; capable of zooming in and out as needed to support tactical execution and high-level planning.

• PMP certification or equivalent.
• Background in biology, genomics, or computational sciences. 
• Prior experience working in biotech, life sciences, or scientific R&D settings.
• Familiarity with ML tools (e.g., MLflow, Kubeflow) and cloud platforms (e.g., GCP).

• A collaborative and innovative environment at the frontier of computational biology, machine learning, and drug discovery. 
• Highly competitive compensation, including meaningful stock ownership.
• Comprehensive benefits - including health, vision, and dental coverage for employees and families, employee and family assistance program. 
• Flexible work environment - including flexible hours, extended long weekends, holiday shutdown, unlimited personal days.
• Maternity and parental leave top-up coverage, as well as new parent paid time off. 
• Focus on learning and growth for all employees - learning and development budget & lunch and learns.
• Facilities located in the heart of Toronto - the epicenter of machine learning and AI research and development, and in Kendall Square, Cambridge, Mass. - a global center of biotechnology and life sciences.

Deep Genomics encourages applications from all backgrounds who seek the opportunity to build the world's leading AI-driven genetic medicine company. 

If you have a disability or special need, accommodation is available on request for candidates taking part in all aspects of the selection process.